COORDINATION BEHAVIOR OF 4-((3-CHLORO-2-METHYLPHENYL) AMINO)BENZOIC ACID TOWARDS CR(III) AND CU(II) IONS: SYNTHESIS, CHARACTERIZATION AND ANTIBACTERIAL ACTIVITY


Monika Chaudhary, Mradula Mittal

ABSTRACT
Cr(III) and Cu(II) complexes (1–6) of general composition M(L1)X2 and M(L1)2 (M=Cr(III), Cu(II), X=Cl-1, NO3-1) with ligand 4-((3-chloro-2-methylphenyl)amino)benzoic acid (HL1) were synthesized. The characterization of newly synthesized ligand and complexes was done by 1H NMR, UV–VIS, IR, Mass spectrophotometry and molar conductivity studies. On the basis of the spectral study, octahedral geometry was assigned to Cr(III) metal complexes. Cu(II) complexes in metal:ligand (1:1)  show square planar geometry and distorted octahedral geometry in metal:ligand (1:2) complexes. All the synthesized compounds were screened for antibacterial activity against the bacterial strains i.e. Escherichia coli and Pseudomonas striata. The antibacterial results reveal that metal complexes show enhance activity as compared to the free ligand.

Key words: Chromium(III), Copper(II), spectral studies, antibacterial screening