Mn(II), Co(II), Ni(II), & Cu(II) COMPLEXES OF NITROGEN AND SULPHUR DONOR LIGAND: SYNTHESIS, SPECTRAL CHARACTERIZATION, MOLECULAR MODELING AND MICROBIOLOGY ACTIVITY


Sulekh Chandra, Seema Gautam, Amit Kumar, Swati Agrawal

ABSTRACT

Mn(II), Co(II), Ni(II) and Cu(II) complexes of nitrogen and sulphur donor atoms containing ligand i.e. 3,3-thiodipropionicacid-bis(5-amino- 1,3,4-thiodiazole-2-thiol) were synthesized and characterized by physical, analytical and spectroscopic methods. Elemental analysis indicated that metal complexes possessed general composition M(L)(NO3)2 and M(L)(SO4), where M = Mn(II), Co(II), Ni(II), Cu(II) and L = ligand. The molar conductance value indicated that metal complexes [M(L)NO3]NO3 and [M(L)SO4] were electrolytic and non- electrolytic in nature, respectively. On the basis of IR Spectral study, it was concluded that ligand contain nitrogen and sulphur donor atoms and these donor atoms coordinated to metal ions and formed metal complexes. All complexes were found to have six-coordinated geometry i.e. Mn(II), Ni(II), Co(II) complexes possessed octahedral geometry, whereas Cu(II)

complexes, distorted octahedral or tetragonal geometry. The covalency factor (β) suggested that all complexes were covalent in nature. Ligand and metal complexes i.e. Mn(II), Co(II), Ni(II) and Cu(II) were screened for their microbiology activity against four fungi i.e. Candida krusei, Candida tropicalis and Candida parapsilosis.

Keywords: ligand, complexes, electrolytic, non- electrolytic, Spectral studies, covalency factor, six-coordinated geometry, microbiology.